I'm often asked which of these are better to use, and it's a hard question to answer. Lattice is probably easier to learn, but once you get over the learning curve ggplot2 has a lot of elegance and power.
To help you decide, the awesome blog Learning R is working through Deepayan Sarkar's book Lattice: Multivariate Graphics with R and is reproducing the graphics therein using ggplot2. This side-by-side comparison of the same graph done in the two packages is a great way to get a sense of the similarities and differences between the two methods, and to help decide which package is right for you. Be sure to check out all the parts in this multi-part series.
Learning R: ggplot2 Version of Figures in “Lattice: Multivariate Data Visualization with R” (Part 1) (Part 2) (Part 3)
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